hrp0089rfc13.6 | Pituitary, Neuroendocrinology and Puberty 2 | ESPE2018

Close Correlation between Salivary and Blood Steroids in Normal Boys: Salivary Testosterone Best Characterizes Male Puberty

Schwab Karl Otfried , Dickhuth Karoline , Mumm Rebekka , Stier Bernhard , Doerfer Juergen , Grueninger Dirk , Brichta Corinna Melanie , van der Werf-Grohmann Natascha , Wurm Michael , Krebs Andreas

Aims: The golden standard to characterize pubertal maturation is the analysis of steroid hormones in the blood. The aim of the investigation was to assess whether the analysis of salivary steroids is similarly able to characterize male pubertal development.Methods: The investigation included 165 normal boys (mean age 12.7±2.8 years, mean body mass index 19.6±4.2 kg/m2). Pubic hair stages were stratified by Tanner and testicular volum...

hrp0082p1-d3-85 | Diabetes (2) | ESPE2014

Algorithm-Based Cholesterol Monitoring in Children with Type 1 Diabetes

Schwab K Otfried , Doerfer Juergen , Scheidt-Nave Christa , Kurth Barbel-Maria , Hungele Andreas , Scheuing Nicole , Krebs Andreas , Dost Axel , Rohrer Tilman R , Schober Edith , Holl Reinhard W

Background: Lipid profiles of type 1 diabetic children are influenced by age, sex, BMI- and HbA1c-values. There is a discrepancy between increased cholesterol levels and the management required. Thus, 26% of patients have dyslipidemia but only 0.4% of them receive lipid lowering medication.Objective and hypothesis: To facilitate child-specific and diabetes-related cholesterol control, we developed a monitoring algorithm derived from population-based refe...

hrp0084p3-702 | Diabetes | ESPE2015

Non-HDL Cholesterol in Diabetic Children: Treatment Recommendations Considering Glycaemic Control, BMI, Age, Gender, and Generally Accepted Cut Points

Schwab Karl Otfried , Doerfer Juergen , Hungele Andreas , Scheuing Nicole , Krebs Andreas , Dost Axel , Rohrer Tilman R , Hofer Sabine , Holl Reinhard W

Background: Non-high-density lipoprotein cholesterol (non-HDL-C) has been shown to be a suitable predictor of cardiovascular risk.Objective and hypotheses: We aimed to investigate factors influencing non-HDL-C levels in children with type 1diabetes (T1D, registered at the German/Austrian DPV database, n=26358) in order to increase the rare use of lipid-lowering therapies. Recommendations for acceptable (<120 mg/dl), borderline-high (120&#150...